Purity ≥ 99%5-Amino-1MQ
NNMT inhibitor (small molecule)Analytical-grade small-molecule reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
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NNMT inhibitor (small molecule)
5-Amino-1MQ
Analytical-grade small-molecule reference material, supplied as a lyophilized powder for in-vitro laboratory research use only.
Free shipping over $149 · CoA included with every order
Est. 2-5 days
Free shipment protection
Overnight shipping available
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Lab Tested by Vanguard · Certificate of Analysis per lot
5-Amino-1MQ
5-Amino-1MQ is supplied as an analytical-grade biochemical reference material for laboratory research use only.
Intended use
Supplied for in-vitro research, analytical method development, identity verification, and laboratory evaluation by qualified research customers.
Restrictions
Not for human or animal consumption. Not for therapeutic, clinical, diagnostic, dietary-supplement, dosing, injection, ingestion, or administration use.
By ordering, the buyer confirms qualified research use and agrees not to use the material for human or animal consumption or administration. Refrigerate upon receipt; keep in a dark environment.
Published research
Selected peer-reviewed literature
Independent published studies on this compound, listed for research reference only. These citations are not claims of any effect; VNG materials are supplied for laboratory research use.
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
Journal of Obstetrics and Gynaecology · PubMed ↗
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
Scientific Reports · PubMed ↗
NAD(+) metabolism enzyme NNMT in cancer-associated fibroblasts drives tumor progression and resistance to immunotherapy
Journal for ImmunoTherapy of Cancer · PubMed ↗
Nicotinamide N-methyl transferase (NNMT): An emerging therapeutic target
Drug Discovery Today · PubMed ↗
Common questions
About this material
Answers describe what the published research examines and where the evidence is limited. They are not claims of any effect; this material is supplied for laboratory research use only.
What is 5-Amino-1MQ?
A small-molecule inhibitor of the enzyme NNMT (nicotinamide N-methyltransferase). It is not a peptide. Supplied here as reference material for laboratory research only.
What is NNMT?
An enzyme that methylates nicotinamide, sitting within NAD+ salvage metabolism. It is notably overexpressed in adipose tissue and in several tumour types, which is why it became a research target.
How strong is the evidence?
Weak, and we would rather say so. There are no human trials. Compound-specific studies number only a handful of cell-line and rodent experiments, and much of the wider literature concerns the NNMT target rather than this molecule.
Is it a peptide?
No. It is a small quinolinium compound. It appears alongside peptides in research contexts because of shared interest in metabolic pathways, not because of any chemical similarity.
How is it stored?
Keep the lyophilized powder cold and dark, refrigerated for short-term or frozen for longer storage; refrigerate once in solution and avoid repeated freeze-thaw.
Full research overview: 5-Amino-1MQ: What It Is and What It Does
5-Amino-1MQ · 5mg
$49
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